Limiting glucose linked to longer cell life

by Staff
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BIRMINGHAM, ALA. — Limiting the consumption of glucose may extend the life of healthy human lung cells and speed the death of precancerous human lung cells, according to researchers at the University of Alabama at Birmingham.

“These results further verify the potential health benefits of controlling calorie intake,” said Trygve Tollefsbol, principal investigator. “Our research indicates that calorie reduction extends the lifespan of healthy human cells and aids the body’s natural ability to kill off cancer-forming cells.”

The researchers conducted tests by growing both healthy human lung cells and precancerous human lung cells in flasks. The flasks were provided either normal levels of glucose or significantly reduced amounts of glucose, and the cells were allowed to grow for a number of weeks.

“In that time, we were able to track the cells’ ability to divide while also monitoring the number of surviving cells,” Dr. Tollefsbol said. “The pattern that was revealed to us showed that restricted glucose levels led the healthy cells to grow longer than is typical and caused precancerous cells to die off in large numbers.”

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